Anti Rabies Serum (Premi-RAB) contains purified enzyme refined equine immunoglobulin fraction – Low Fc content minimizes possibility of anaphylactic reactions.
Mainly administered for passive immunity to the patients being bitten and scratched by rabies or other animals carrying rabies virus.
(Enzyme refined equine immunoglobulins) – Liquid
Each ml of Rabies Anti Serum contains not less than 300 I.U.
Phenol (Preservative) - NMT 0.25% w/v
Glycine I.P. - Stabilizer
Sodium Chloride I.P. - Excipient
Rabies Antiserum should be given immediately after the bite preferably within 24 hours of animal bite to get maximum benefit. It can be administered up to 7 days after administration of first dose of vaccine. Recommended dose is 40 IU/kg body weight up to a maximum of 3000 I.U. Children and adults to receive the same dose of 40 IU/kg. of body weight. As much of the calculated dose as anatomically feasible should be infiltrated into and around the wounds. The rest of the dose should be given intramuscularly as a single dose (in the gluteal region) followed by a complete course of vaccine, but in a different part of the body (upper part of arms, deltoid region). If calculated dose is insufficient to infiltrate all wounds, It can be diluted in Normal saline 2-3 folds. Immunocompromised / immunosupressed individuals even with Category II exposures need Rabies Antiserum.
It should be stored at +2˚ to + 8˚ C. Do not freeze and keep protected from heat.